A Magnet for Industry Leaders

Missouri is home to a diverse range of businesses, from Fortune 500 companies to thriving small and medium-sized enterprises. 

Our strategic location in the Midwest combined with robust infrastructure, a strong workforce, and our low-cost, business-friendly environment has long been attracting companies from across the country and the world.

A Well-Connected Hub of Innovators

Companies in Missouri know that the more quality people, businesses, and support systems you surround yourself with, the more likely you are to succeed. 

When you relocate or expand your business to Missouri, you’re joining a community filled with thriving organizations driving innovations across various major industries, including manufacturing, r&d, corporate services, and distribution.

Local Comfort with International Reach

Companies in Missouri harness the state’s unique advantages to break through to new markets, expand their customer base, and collaborate with industry-leading partners. 

From the largest companies in Missouri to new start-ups, businesses are making their homes in bustling urban environments like St. Louis, Springfield or Kansas City, as well as in more rural areas just beyond the city limits.

With a centralized site location, numerous business-friendly tax incentives, and a deep, experienced pool of talent, you won’t find a better place to move forward and reach your goals.

Find the Perfect Location For Your Business

When you’re ready to join companies in Missouri, our team will help foster your growth and make your transition as smooth and seamless as possible.

Whether it’s identifying available real estate, finding skilled talent or any other service you need for success, Missouri Partnership can provide it. Contact us to find out why so many world-class companies are proud to call Missouri home.

Global Leaders Operating in Missouri

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 BOEING is a trademark of Boeing Management Company. Copyright © 2009 Boeing. All rights reserved.

Largest Companies in Missouri

Missouri is proud to host some of the most well-known companies in the world. These companies span multiple industries, including healthcare, manufacturing, and financial services. 

Below are a few of the largest companies in Missouri:

• Boeing Defense, Space & Security
  Boeing’s defense division is a significant employer in Missouri, particularly in the St. Louis region. With its focus on aerospace and defense, Boeing provides high-tech jobs and supports the state’s position as a leader in innovation and advanced manufacturing.
  
• Centene Corporation
  Based in St. Louis, Centene Corporation is a leader in healthcare solutions, specializing in government-sponsored healthcare programs. As one of the largest healthcare companies in the U.S., Centene continues to expand its operations, providing essential healthcare services and creating jobs in Missouri and beyond.
  
• Emerson Electric Co.
  Headquartered in Ferguson, Missouri, Emerson is a global leader in engineering and technology. The company provides innovative solutions for industrial, commercial, and residential applications, and is one of the top companies in Missouri, contributing to the state’s industrial strength.
  
• Ford
  Ford’s Kansas City assembly plant is one of the company’s largest and most productive manufacturing facilities. The plant produces the best-selling Ford F-150 and the Transit van, supporting thousands of jobs in the region. Ford’s ongoing investment in the Kansas City area continues to advance Missouri as a hub for the automotive industry.
  
• O’Reilly Automotive
  Founded in Springfield, Missouri, O’Reilly Automotive is one of the nation’s largest suppliers of automotive parts, tools, and accessories. The company operates thousands of retail locations across the country, making it a key player in Missouri’s economy and one of its largest companies.

Largest Employers in Missouri

Missouri’s economy is supported by a number of large employers that provide thousands of jobs across the state. These employers benefit from Missouri’s expansive talent pool, easily finding professionals to build effective teams. 

Some of the largest employers in Missouri include:

• BJC HealthCare
  BJC HealthCare is a major healthcare provider in Missouri, based in St. Louis. With a network of hospitals, clinics and specialized care centers, BJC HealthCare employs tens of thousands of healthcare professionals and staff, making it one of Missouri’s largest employers.
  
• Mercy Health System
  Mercy Health operates hospitals, outpatient centers, and healthcare facilities across Missouri. As one of the largest employers in the state, Mercy Health plays a key role in providing healthcare services while tapping into the state’s skilled healthcare workforce.
  
• SSM Healthcare System
  SSM Health includes a comprehensive network of hospitals, clinics, and healthcare facilities across the state. Headquartered in St. Louis, SSM Health employs thousands of healthcare professionals dedicated to providing high-quality, compassionate care to communities throughout Missouri.
  
• University of Missouri System
  The University of Missouri System, with campuses in Columbia, Kansas City, Rolla, and St. Louis, is one of the state’s largest employers in the education sector. It provides employment opportunities for faculty, staff, researchers, and administrators, contributing to Missouri’s role as a leader in higher education.
  
• Washington University
  Located in St. Louis, Washington University (Wash U) is one of Missouri’s largest employers, with a workforce that spans academics, healthcare, and research. Drawing faculty, staff, and healthcare experts from across the country, Wash U contributes significantly to Missouri’s economy and bolsters the local workforce through its impact in higher education, research, and patient care.
  
• Walmart
  As the nation’s largest retailer, Walmart operates numerous distribution centers, offices and stores throughout Missouri. With thousands of employees, Walmart is one of the largest employers in the state, providing jobs in both urban and rural areas.